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SOCS, Intrinsic Virulence Factors, and Treatment of COVID-19

The suppressor of cytokine signaling (SOCS) family of intracellular checkpoint inhibitors has received little recognition compared to other checkpoint inhibitors. Two members of this family, SOCS1 and SOCS3, are indispensable, since SOCS1 knockout in mice results in neonatal death due to interferon...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Johnson, Howard M., Lewin, Alfred S., Ahmed, Chulbul M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644869/
https://ncbi.nlm.nih.gov/pubmed/33193390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.582102
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