A primer set for the rapid isolation of scFv fragments against cell surface antigens from immunised rats

Antibody phage display is a powerful platform for discovery of clinically applicable high affinity monoclonal antibodies against a broad range of targets. Libraries generated from immunized animals offer the advantage of in vivo affinity-maturation of V regions prior to library generation. Despite a...

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Udgivet i:Sci Rep
Main Authors: Nannini, Francesco, Parekh, Farhaan, Wawrzyniecka, Patrycja, Mekkaoui, Leila, Righi, Matteo, Dastjerdi, Fatemeh V., Yeung, Jenny, Roddie, Claire, Bai, Yuchen, Ma, Biao, Ferrari, Mathieu, Onuoha, Shimobi, Chester, Kerry, Pule, Martin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644676/
https://ncbi.nlm.nih.gov/pubmed/33154441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76069-3
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