Combining phage display with SMRTbell next-generation sequencing for the rapid discovery of functional scFv fragments

Phage display technology in combination with next-generation sequencing (NGS) currently is a state-of-the-art method for the enrichment and isolation of monoclonal antibodies from diverse libraries. However, the current NGS methods employed for sequencing phage display libraries are limited by the s...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Nannini, Francesco, Senicar, Lenart, Parekh, Farhaan, Kong, Khai J., Kinna, Alexander, Bughda, Reyisa, Sillibourne, James, Hu, Xihao, Ma, Biao, Bai, Yuchen, Ferrari, Mathieu, Pule, Martin A., Onuoha, Shimobi C.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7781620/
https://ncbi.nlm.nih.gov/pubmed/33382949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2020.1864084
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