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Synthesis of novel 4-methylthiocoumarin and comparison with conventional coumarin derivative as a multi-target-directed ligand in Alzheimer’s disease

Alzheimer’s disease (AD) is a multifactorial disorder characterized by cognitive deficit and memory loss. The pathological feature of the disease involves β-amyloid senile plaques, reduced levels of acetylcholine neurotransmitter, oxidative stress and neurofibrillary tangles formation within the bra...

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Библиографические подробности
Опубликовано в: :3 Biotech
Главные авторы: Kumar, Shivani, Tyagi, Yogesh Kumar, Kumar, Manoj, Kumar, Suresh
Формат: Artigo
Язык:Inglês
Опубликовано: Springer International Publishing 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644673/
https://ncbi.nlm.nih.gov/pubmed/33184595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13205-020-02481-1
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