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Multi-Target Directed Donepezil-Like Ligands for Alzheimer's Disease
HIGHLIGHTS: ASS234 is a MTDL compound containing a moiety from Donepezil and the propargyl group from the PF 9601N, a potent and selective MAO B inhibitor. This compound is the most advanced anti-Alzheimer agent for preclinical studies identified in our laboratory. Derived from ASS234 both multipote...
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| Publicado no: | Front Neurosci |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4879129/ https://ncbi.nlm.nih.gov/pubmed/27252617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00205 |
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