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Design and Synthesis of Ranitidine Analogs as Multi-Target Directed Ligands for the Treatment of Alzheimer’s Disease

The aggregation of amyloid β (Aβ) peptides and deposition of amyloid plaques are implicated in the pathogenesis of Alzheimer’s disease (AD). Therefore, blocking Aβ aggregation with small molecules has been proposed as one therapeutic approach for AD. In the present study, a series of ranitidine anal...

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Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Gao, Jie, Suo, Chen, Tseng, Jui-Heng, Moss, Melissa A., Terry, Alvin V., Chapman, James
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8003314/
https://ncbi.nlm.nih.gov/pubmed/33803769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22063120
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