GDC-0349 inhibits non-small cell lung cancer cell growth

Non-small cell lung cancer (NSCLC) is a leading cause of cancer-related human mortality with a clear need for new therapeutic intervention. GDC-0349 is a potent and selective ATP-competitive mTOR inhibitor. In A549 cells and primary human NSCLC cells, GDC-0349 inhibited cell growth, proliferation, c...

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Detaylı Bibliyografya
Yayımlandı:Cell Death Dis
Asıl Yazarlar: Yang, Han, Zhao, Jun, Zhao, Mengjing, Zhao, Lihao, Zhou, Li-na, Duan, Yuxia, Li, Gang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644631/
https://ncbi.nlm.nih.gov/pubmed/33154352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03146-w
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