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GDC-0349 inhibits non-small cell lung cancer cell growth
Non-small cell lung cancer (NSCLC) is a leading cause of cancer-related human mortality with a clear need for new therapeutic intervention. GDC-0349 is a potent and selective ATP-competitive mTOR inhibitor. In A549 cells and primary human NSCLC cells, GDC-0349 inhibited cell growth, proliferation, c...
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| Udgivet i: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7644631/ https://ncbi.nlm.nih.gov/pubmed/33154352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03146-w |
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