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Telomerase biogenesis requires a novel Mex67 function and a cytoplasmic association with the Sm(7) complex

The templating RNA is the core of the telomerase reverse transcriptase. In Saccharomyces cerevisiae, the complex life cycle and maturation of telomerase includes a cytoplasmic stage. However, timing and reason for this cytoplasmic passage are poorly understood. Here, we use inducible RNA tagging exp...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Vasianovich, Yulia, Bajon, Emmanuel, Wellinger, Raymund J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644208/
https://ncbi.nlm.nih.gov/pubmed/33095156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60000
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