Crimean-Congo Hemorrhagic Fever Virus Subunit Vaccines Induce High Levels of Neutralizing Antibodies But No Protection in STAT1 Knockout Mice

Crimean-Congo hemorrhagic fever virus is a tick-borne bunyavirus of the Nairovirus genus that causes hemorrhagic fever in humans with high case fatality. Here, we report the development of subunit vaccines and their efficacy in signal transducer and activator of transcription 1 (STAT1) knockout mice...

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Detalhes bibliográficos
Publicado no:Vector Borne Zoonotic Dis
Main Authors: Kortekaas, Jeroen, Vloet, Rianka P.M., McAuley, Alexander J., Shen, Xiaoli, Bosch, Berend Jan, de Vries, Laura, Moormann, Rob J.M., Bente, Dennis A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7643766/
https://ncbi.nlm.nih.gov/pubmed/26684523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/vbz.2015.1855
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