Expression of interferon-induced antiviral genes is delayed in a STAT1 knockout mouse model of Crimean-Congo hemorrhagic fever

<p>Abstract</p> <p>Background</p> <p>Crimean Congo hemorrhagic fever (CCHF) is a tick-borne hemorrhagic zoonosis associated with high mortality. Pathogenesis studies and the development of vaccines and antivirals against CCHF have been severely hampered by the lack of s...

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Detalhes bibliográficos
Main Authors: Bowick Gavin C, Airo Adriana M, Bente Dennis A
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2012-06-01
Colecção:Virology Journal
Assuntos:
Crimean Congo hemorrhagic fever
Interferon
Animal model
Signaling
STAT1
Acesso em linha:http://www.virologyj.com/9/1/122
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