Pathogenesis and Immune Response of Crimean-Congo Hemorrhagic Fever Virus in a STAT-1 Knockout Mouse Model

Tick-borne Crimean-Congo hemorrhagic fever virus (CCHFV) causes a severe hemorrhagic syndrome in humans but not in its vertebrate animal hosts. The pathogenesis of the disease is largely not understood due to the lack of an animal model. Laboratory animals typically show no overt signs of disease. H...

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Detalhes bibliográficos
Principais autores: Bente, Dennis A., Alimonti, Judie B., Shieh, Wun-Ju, Camus, Gaëlle, Ströher, Ute, Zaki, Sherif, Jones, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953203/
https://ncbi.nlm.nih.gov/pubmed/20739514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01383-10
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