Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons

The chromatin landscape of human brain cells encompasses key information to understanding brain function. Here we use ATAC-seq to profile the chromatin structure in four distinct populations of cells (glutamatergic neurons, GABAergic neurons, oligodendrocytes, and microglia/astrocytes) from three di...

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Publicat a:Nat Commun
Autors principals: Hauberg, Mads E., Creus-Muncunill, Jordi, Bendl, Jaroslav, Kozlenkov, Alexey, Zeng, Biao, Corwin, Chuhyon, Chowdhury, Sarah, Kranz, Harald, Hurd, Yasmin L., Wegner, Michael, Børglum, Anders D., Dracheva, Stella, Ehrlich, Michelle E., Fullard, John F., Roussos, Panos
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7643171/
https://ncbi.nlm.nih.gov/pubmed/33149216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19319-2
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