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Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons

The chromatin landscape of human brain cells encompasses key information to understanding brain function. Here we use ATAC-seq to profile the chromatin structure in four distinct populations of cells (glutamatergic neurons, GABAergic neurons, oligodendrocytes, and microglia/astrocytes) from three di...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Hauberg, Mads E., Creus-Muncunill, Jordi, Bendl, Jaroslav, Kozlenkov, Alexey, Zeng, Biao, Corwin, Chuhyon, Chowdhury, Sarah, Kranz, Harald, Hurd, Yasmin L., Wegner, Michael, Børglum, Anders D., Dracheva, Stella, Ehrlich, Michelle E., Fullard, John F., Roussos, Panos
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7643171/
https://ncbi.nlm.nih.gov/pubmed/33149216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19319-2
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