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Striatal H3K27 acetylation linked to glutamatergic gene dysregulation in human heroin abusers holds promise as therapeutic target
BACKGROUND: Opiate abuse and overdose reached epidemic levels in the USA. However, despite significant advances in animal and in vitro models, little knowledge has been directly accrued regarding the neurobiology of the opiate-addicted human brain. METHODS: We used post-mortem human brain specimens...
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| Publicado no: | Biol Psychiatry |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5346335/ https://ncbi.nlm.nih.gov/pubmed/27863698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2016.09.015 |
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