Nalaganje...
Pan-cancer landscape of homologous recombination deficiency
Homologous recombination deficiency (HRD) results in impaired double strand break repair and is a frequent driver of tumorigenesis. Here, we develop a genome-wide mutational scar-based pan-cancer Classifier of HOmologous Recombination Deficiency (CHORD) that can discriminate BRCA1- and BRCA2-subtype...
Shranjeno v:
| izdano v: | Nat Commun |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2020
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7643118/ https://ncbi.nlm.nih.gov/pubmed/33149131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19406-4 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|