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Biomarkers for Homologous Recombination Deficiency in Cancer
DNA double-strand breaks foster tumorigenesis and cell death. Two distinct mechanisms can be activated by the cell for DNA repair: the accurate mechanism of homologous recombination repair or the error-prone non-homologous end joining. Homologous Recombination Deficiency (HRD) is associated with sen...
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| Publicado no: | J Pers Med |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8304859/ https://ncbi.nlm.nih.gov/pubmed/34203281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm11070612 |
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