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SMN protein promotes membrane compartmentalization of ribosomal protein S6 transcript in human fibroblasts
Alterations of RNA homeostasis can lead to severe pathological conditions. The Survival of Motor Neuron (SMN) protein, which is reduced in Spinal Muscular Atrophy, impacts critical aspects of the RNA life cycle, such as splicing, trafficking, and translation. Increasing evidence points to a potentia...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7643083/ https://ncbi.nlm.nih.gov/pubmed/33149163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76174-3 |
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