SMN protein promotes membrane compartmentalization of ribosomal protein S6 transcript in human fibroblasts

Alterations of RNA homeostasis can lead to severe pathological conditions. The Survival of Motor Neuron (SMN) protein, which is reduced in Spinal Muscular Atrophy, impacts critical aspects of the RNA life cycle, such as splicing, trafficking, and translation. Increasing evidence points to a potentia...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Gabanella, Francesca, Onori, Annalisa, Ralli, Massimo, Greco, Antonio, Passananti, Claudio, Di Certo, Maria Grazia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7643083/
https://ncbi.nlm.nih.gov/pubmed/33149163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76174-3
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