SMN protein promotes membrane compartmentalization of ribosomal protein S6 transcript in human fibroblasts

Alterations of RNA homeostasis can lead to severe pathological conditions. The Survival of Motor Neuron (SMN) protein, which is reduced in Spinal Muscular Atrophy, impacts critical aspects of the RNA life cycle, such as splicing, trafficking, and translation. Increasing evidence points to a potentia...

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Publicado en:Sci Rep
Main Authors: Gabanella, Francesca, Onori, Annalisa, Ralli, Massimo, Greco, Antonio, Passananti, Claudio, Di Certo, Maria Grazia
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7643083/
https://ncbi.nlm.nih.gov/pubmed/33149163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76174-3
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