Novel Adeno-Associated Viral Vector Delivering the Utrophin Gene Regulator Jazz Counteracts Dystrophic Pathology in mdx Mice

Over-expression of the dystrophin-related gene utrophin represents a promising therapeutic strategy for Duchenne muscular dystrophy (DMD). The strategy is based on the ability of utrophin to functionally replace defective dystrophin. We developed the artificial zinc finger transcription factor “Jazz...

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Foilsithe in:J Cell Physiol
Main Authors: Strimpakos, Georgios, Corbi, Nicoletta, Pisani, Cinzia, Di Certo, Maria Grazia, Onori, Annalisa, Luvisetto, Siro, Severini, Cinzia, Gabanella, Francesca, Monaco, Lucia, Mattei, Elisabetta, Passananti, Claudio
Formáid: Artigo
Teanga:Inglês
Foilsithe: BlackWell Publishing Ltd 2014
Ábhair:
Original Research Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303978/
https://ncbi.nlm.nih.gov/pubmed/24469912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24567
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