Novel Adeno-Associated Viral Vector Delivering the Utrophin Gene Regulator Jazz Counteracts Dystrophic Pathology in mdx Mice

Over-expression of the dystrophin-related gene utrophin represents a promising therapeutic strategy for Duchenne muscular dystrophy (DMD). The strategy is based on the ability of utrophin to functionally replace defective dystrophin. We developed the artificial zinc finger transcription factor “Jazz...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: Strimpakos, Georgios, Corbi, Nicoletta, Pisani, Cinzia, Di Certo, Maria Grazia, Onori, Annalisa, Luvisetto, Siro, Severini, Cinzia, Gabanella, Francesca, Monaco, Lucia, Mattei, Elisabetta, Passananti, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Original Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303978/
https://ncbi.nlm.nih.gov/pubmed/24469912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24567
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