Inhibition of AURKB, regulated by pseudogene MTND4P12, confers synthetic lethality to PARP inhibition in skin cutaneous melanoma

Despite significant advances, skin cutaneous melanoma (SKCM) is a common life-threatening cancer worldwide. Recently, pseudogenes have been discovered to be functional in many physiological processes and the pathogenesis of various diseases, including cancer. However, their relevance to SKCM remains...

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Bibliografiske detaljer
Udgivet i:Am J Cancer Res
Main Authors: Guo, Yan, Wei, Qi, Tan, Linghui, Li, Yadan, Li, Jingyi, Li, Ling, Jiang, Tingting, Zhang, Shuzhen, Jin, Hongchuan
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2020
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7642665/
https://ncbi.nlm.nih.gov/pubmed/33163283
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