Glial metabolic rewiring promotes axon regeneration and functional recovery in the central nervous system

Axons in the mature central nervous system (CNS) fail to regenerate after axotomy, partly due to the inhibitory environment constituted by reactive glial cells producing astrocytic scars, chondroitin sulfate proteoglycans and myelin debris. We investigated this inhibitory milieu, showing it is rever...

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Gepubliceerd in:Cell Metab
Hoofdauteurs: Li, Feng, Sami, Armin, Noristani, Harun N., Slattery, Kieran, Qiu, Jingyun, Groves, Thomas, Wang, Shuo, Veerasammy, Kelly, Chen, Yuki X., Morales, Jorge, Haynes, Paula, Sehgal, Amita, He, Ye, Li, Shuxin, Song, Yuanquan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7642184/
https://ncbi.nlm.nih.gov/pubmed/32941799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.08.015
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