Promoting Axon Regeneration in Adult CNS by Targeting Liver Kinase B1

Liver kinase B1 (LKB1), a downstream effector of cyclic AMP (cAMP)/PKA and phosphatidylinositol 3-kinase (PI3K) pathways, is a determinant for migration and differentiation of many cells, but its role in CNS axon regeneration is unknown. Therefore, LKB1 was overexpressed in sensorimotor cortex of ad...

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Publicat a:Mol Ther
Autors principals: Ohtake, Yosuke, Sami, Armin, Jiang, Xinpei, Horiuchi, Makoto, Slattery, Kieran, Ma, Lena, Smith, George M., Selzer, Michael E., Muramatsu, Shin-ichi, Li, Shuxin
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2019
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319317/
https://ncbi.nlm.nih.gov/pubmed/30509565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.10.019
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