Discrete Adaptive Responses to MEK Inhibitor in Subpopulations of Triple-Negative Breast Cancer

Triple-negative breast cancers contain a spectrum of epithelial and mesenchymal phenotypes. SUM-229PE cells represent a model for this heterogeneity, maintaining both epithelial and mesenchymal subpopulations that are genomically similar but distinct in gene expression profiles. We identified differ...

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Gepubliceerd in:Mol Cancer Res
Hoofdauteurs: Goulet, Daniel R., Foster, Joseph P., Zawistowski, Jon S., Bevill, Samantha M., Noël, Mélodie P., Olivares-Quintero, José F., Sciaky, Noah, Singh, Darshan, Santos, Charlene, Pattenden, Samantha G., Davis, Ian J., Johnson, Gary L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7642176/
https://ncbi.nlm.nih.gov/pubmed/32753473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-1011
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