A Shaking-Culture Method for Generating Bone Marrow Derived Mesenchymal Stromal/Stem Cell-Spheroids With Enhanced Multipotency in vitro

Mesenchymal stromal/stem cells (MSCs), which generally expand into adherent monolayers, readily lose their proliferative and multilineage potential following repeated passages. Floating culture systems can be used to generate MSC spheroids, which are expected to overcome limitations associated with...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Bioeng Biotechnol
Main Authors: Niibe, Kunimichi, Ohori-Morita, Yumi, Zhang, Maolin, Mabuchi, Yo, Matsuzaki, Yumi, Egusa, Hiroshi
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Bioengineering and Biotechnology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641632/
https://ncbi.nlm.nih.gov/pubmed/33195156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.590332
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