Notch2 Signaling Regulates the Proliferation of Murine Bone Marrow-Derived Mesenchymal Stem/Stromal Cells via c-Myc Expression

Mesenchymal stem/stromal cells (MSCs) reside in the bone marrow and maintain their stemness under hypoxic conditions. However, the mechanism underlying the effects of hypoxia on MSCs remains to be elucidated. This study attempted to uncover the signaling pathway of MSC proliferation. Under low-oxyge...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Sato, Yukio, Mabuchi, Yo, Miyamoto, Kenichi, Araki, Daisuke, Niibe, Kunimichi, Houlihan, Diarmaid D., Morikawa, Satoru, Nakagawa, Taneaki, Nakajima, Toshihiro, Akazawa, Chihiro, Hori, Shingo, Okano, Hideyuki, Matsuzaki, Yumi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113929/
https://ncbi.nlm.nih.gov/pubmed/27855169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165946
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