Notch2 Signaling Regulates the Proliferation of Murine Bone Marrow-Derived Mesenchymal Stem/Stromal Cells via c-Myc Expression

Mesenchymal stem/stromal cells (MSCs) reside in the bone marrow and maintain their stemness under hypoxic conditions. However, the mechanism underlying the effects of hypoxia on MSCs remains to be elucidated. This study attempted to uncover the signaling pathway of MSC proliferation. Under low-oxyge...

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Pubblicato in:PLoS One
Autori principali: Sato, Yukio, Mabuchi, Yo, Miyamoto, Kenichi, Araki, Daisuke, Niibe, Kunimichi, Houlihan, Diarmaid D., Morikawa, Satoru, Nakagawa, Taneaki, Nakajima, Toshihiro, Akazawa, Chihiro, Hori, Shingo, Okano, Hideyuki, Matsuzaki, Yumi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113929/
https://ncbi.nlm.nih.gov/pubmed/27855169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165946
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