Notch2 Signaling Regulates the Proliferation of Murine Bone Marrow-Derived Mesenchymal Stem/Stromal Cells via c-Myc Expression

Mesenchymal stem/stromal cells (MSCs) reside in the bone marrow and maintain their stemness under hypoxic conditions. However, the mechanism underlying the effects of hypoxia on MSCs remains to be elucidated. This study attempted to uncover the signaling pathway of MSC proliferation. Under low-oxyge...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sato, Yukio, Mabuchi, Yo, Miyamoto, Kenichi, Araki, Daisuke, Niibe, Kunimichi, Houlihan, Diarmaid D., Morikawa, Satoru, Nakagawa, Taneaki, Nakajima, Toshihiro, Akazawa, Chihiro, Hori, Shingo, Okano, Hideyuki, Matsuzaki, Yumi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113929/
https://ncbi.nlm.nih.gov/pubmed/27855169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165946
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