Notch2 Signaling Regulates the Proliferation of Murine Bone Marrow-Derived Mesenchymal Stem/Stromal Cells via c-Myc Expression

Mesenchymal stem/stromal cells (MSCs) reside in the bone marrow and maintain their stemness under hypoxic conditions. However, the mechanism underlying the effects of hypoxia on MSCs remains to be elucidated. This study attempted to uncover the signaling pathway of MSC proliferation. Under low-oxyge...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Sato, Yukio, Mabuchi, Yo, Miyamoto, Kenichi, Araki, Daisuke, Niibe, Kunimichi, Houlihan, Diarmaid D., Morikawa, Satoru, Nakagawa, Taneaki, Nakajima, Toshihiro, Akazawa, Chihiro, Hori, Shingo, Okano, Hideyuki, Matsuzaki, Yumi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113929/
https://ncbi.nlm.nih.gov/pubmed/27855169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165946
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