A Shaking-Culture Method for Generating Bone Marrow Derived Mesenchymal Stromal/Stem Cell-Spheroids With Enhanced Multipotency in vitro

Mesenchymal stromal/stem cells (MSCs), which generally expand into adherent monolayers, readily lose their proliferative and multilineage potential following repeated passages. Floating culture systems can be used to generate MSC spheroids, which are expected to overcome limitations associated with...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Niibe, Kunimichi, Ohori-Morita, Yumi, Zhang, Maolin, Mabuchi, Yo, Matsuzaki, Yumi, Egusa, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Bioengineering and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641632/
https://ncbi.nlm.nih.gov/pubmed/33195156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.590332
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