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Reconstitution of the human tRNA splicing endonuclease complex: insight into the regulation of pre-tRNA cleavage
The splicing of tRNA introns is a critical step in pre-tRNA maturation. In archaea and eukaryotes, tRNA intron removal is catalyzed by the tRNA splicing endonuclease (TSEN) complex. Eukaryotic TSEN is comprised of four core subunits (TSEN54, TSEN2, TSEN34 and TSEN15). The human TSEN complex addition...
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| Foilsithe in: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Oxford University Press
2020
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7641302/ https://ncbi.nlm.nih.gov/pubmed/32476018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa438 |
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