Reconstitution of the human tRNA splicing endonuclease complex: insight into the regulation of pre-tRNA cleavage

The splicing of tRNA introns is a critical step in pre-tRNA maturation. In archaea and eukaryotes, tRNA intron removal is catalyzed by the tRNA splicing endonuclease (TSEN) complex. Eukaryotic TSEN is comprised of four core subunits (TSEN54, TSEN2, TSEN34 and TSEN15). The human TSEN complex addition...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Nucleic Acids Res
Huvudupphovsmän: Hayne, Cassandra K, Schmidt, Casey A, Haque, Maira I, Matera, A Gregory, Stanley, Robin E
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2020
Ämnen:
NAR Breakthrough Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641302/
https://ncbi.nlm.nih.gov/pubmed/32476018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa438
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk