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Avatar pre-tRNAs help elucidate the properties of tRNA-splicing endonucleases that produce tRNA from permuted genes

Unusual tRNA genes, found in some algae, have their mature terminal 3′ portion in front of their 5′ portion in the genome. The transcripts from such genes must be cleaved by a pre-tRNA endonuclease to form a functional tRNA. We present a mechanism for the generation of “corrected” tRNAs from such a...

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Bibliografiske detaljer
Main Authors: Tocchini-Valentini, Giuseppe D., Tocchini-Valentini, Glauco P.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535657/
https://ncbi.nlm.nih.gov/pubmed/23236183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219336110
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