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Avatar pre-tRNAs help elucidate the properties of tRNA-splicing endonucleases that produce tRNA from permuted genes

Unusual tRNA genes, found in some algae, have their mature terminal 3′ portion in front of their 5′ portion in the genome. The transcripts from such genes must be cleaved by a pre-tRNA endonuclease to form a functional tRNA. We present a mechanism for the generation of “corrected” tRNAs from such a...

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Main Authors: Tocchini-Valentini, Giuseppe D., Tocchini-Valentini, Glauco P.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535657/
https://ncbi.nlm.nih.gov/pubmed/23236183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219336110
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