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Cis- and trans-splicing of mRNAs mediated by tRNA sequences in eukaryotic cells
The formation of chimeric mRNAs is a strategy used by human cells to increase the complexity of their proteome, as revealed by the ENCODE project. Here, we use Saccharomyces cerevisiae to show a way by which trans-spliced mRNAs can be generated. We demonstrate that a pretRNA inserted into a premRNA...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2383978/ https://ncbi.nlm.nih.gov/pubmed/18458335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800420105 |
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