Tumor subtype determines therapeutic response to chimeric polypeptide nanoparticle-based chemotherapy in Pten-deleted mouse models of sarcoma

PURPOSE: Nanoparticle-encapsulated drug formulations can improve responses to conventional chemotherapy by increasing drug retention within the tumor and by promoting a more effective anti-tumor immune response than free drug. New drug delivery modalities are needed in sarcomas because they are ofte...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Dodd, Rebecca D., Scherer, Amanda, Huang, Wesley, McGivney, Gavin R., Gutierrez, Wade R., Laverty, Emily, Ashcraft, Kathleen A., Stephens, Victoria R., Yousefpour, Parisa, Saha, Soumen, Knepper-Adrian, Vickie, Floyd, Warren, Chen, Mark, Ma, Yan, Mastria, Eric M., Cardona, Diana M., Eward, William C., Chilkoti, Ashutosh, Kirsch, David G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641033/
https://ncbi.nlm.nih.gov/pubmed/32718998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-2597
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