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Doxorubicin-conjugated chimeric polypeptide nanoparticles that respond to mild hyperthermia
This paper reports the design, physicochemical characterization and in vitro cytotoxicity of a thermally responsive chimeric polypeptide (CP), derived from an elastin-like polypeptide (ELP). The CP self-assembles into ~40 nm diameter nanoparticles upon conjugation of multiple copies of doxorubicin (...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3348377/ https://ncbi.nlm.nih.gov/pubmed/22421424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.02.030 |
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