Divergent immune landscapes of primary and syngeneic Kras-driven mouse tumor models

Immune cells play critical functions in cancer, and mice with intact immune systems are vital to understanding tumor immunology. Both genetically engineered mouse models (GEMMs) and syngeneic cell transplant approaches use immunocompetent mice to define immune-dependent events in tumor development a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gutierrez, Wade R., Scherer, Amanda, McGivney, Gavin R., Brockman, Qierra R., Knepper-Adrian, Vickie, Laverty, Emily A., Roughton, Grace A., Dodd, Rebecca D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7806664/
https://ncbi.nlm.nih.gov/pubmed/33441747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80216-1
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