Detachment Activated CyPA/CD147 Induces Cancer Stem Cell Potential in Non-stem Breast Cancer Cells

BACKGROUND: Cancer stem cells (CSCs), responsible for cancer metastasis and recurrence, are generated from non-CSCs after chemo-radiation therapy. This study investigated the induction of CSC potential in non-stem breast cancer cells and the underlying molecular mechanisms in detachment culture. MET...

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Bibliographic Details
Published in:Front Cell Dev Biol
Main Authors: Meng, Yao, Fan, Xin-Yu, Yang, Li-Jun, Xu, Bao-Qing, He, Duo, Xu, Zhe, Wu, Dong, Wang, Bin, Cui, Hong-Yong, Wang, Shi-Jie, Wang, Li-Juan, Wu, Xiao-Qing, Jiang, Jian-Li, Xu, Liang, Chen, Zhi-Nan, Li, Ling
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Cell and Developmental Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7640948/
https://ncbi.nlm.nih.gov/pubmed/33195186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.543856
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