Simvastatin attenuated rat thoracic aorta remodeling by decreasing ROCK2-mediated CyPA secretion and CD147-ERK1/2-cyclin pathway

Reactive oxygen species-induced cyclophilin A (CyPA) release from vascular smooth muscle cells (VSMCs) may be inhibited by simvastatin in vitro. The present study aimed to further examine the effect of simvastatin on serum CyPA levels and the basigin (CD147)-extracellular signal-regulated kinase (ER...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Mol Med Rep
Glavni autori: Tang, Fu-Cai, Wang, Hong-Yan, Ma, Ming-Ming, Guan, Tian-Wang, Pan, Long, Yao, Dun-Chen, Chen, Ya-Lan, Li, Sheng-Jie, Yang, Hang, Zhu, Xiao-Qin, Tu, Yong-Sheng
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2017
Teme:
Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5779895/
https://ncbi.nlm.nih.gov/pubmed/28983618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.7640
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items