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Less mechanical loading attenuates osteoarthritis by reducing cartilage degeneration, subchondral bone remodelling, secondary inflammation, and activation of NLRP3 inflammasome
AIMS: Osteoarthritis (OA) is a disabling joint disorder and mechanical loading is an important pathogenesis. This study aims to investigate the benefits of less mechanical loading created by intermittent tail suspension for knee OA. METHODS: A post-traumatic OA model was established in 20 rats (12 w...
שמור ב:
| הוצא לאור ב: | Bone Joint Res |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
The British Editorial Society of Bone & Joint Surgery
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7640939/ https://ncbi.nlm.nih.gov/pubmed/33399476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1302/2046-3758.910.BJR-2019-0368.R2 |
| תגים: |
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