Strontium ranelate reduces cartilage degeneration and subchondral bone remodeling in rat osteoarthritis model

AIM: To investigate whether strontium ranelate (SR), a new antiosteoporotic agent, could attenuate cartilage degeneration and subchondral bone remodeling in osteoarthritis (OA). METHODS: Medial meniscal tear (MMT) operation was performed in adult SD rats to induce OA. SR (625 or 1800 mg·kg(−1)·d(−1)...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yu, De-gang, Ding, Hui-feng, Mao, Yuan-qing, Liu, Ming, Yu, Bo, Zhao, Xin, Wang, Xiao-qing, Li, Yang, Liu, Guang-wang, Nie, Shao-bo, Liu, Shen, Zhu, Zhen-an
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2013
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002491/
https://ncbi.nlm.nih.gov/pubmed/23334238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.167
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