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Fragile site instability: measuring more than breaks
Genome instability is not only a hallmark of cancer, it is necessary for its initiation and evolution, and naturally accumulates as cells age. Replication stress is a potent source of genome instability found in many tumor types [1]. Chromosomal fragile sites are genomic loci highly prone to DNA dam...
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| Publicado no: | Oncoscience |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7640903/ https://ncbi.nlm.nih.gov/pubmed/33195735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncoscience.513 |
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