Increased hippocampal TrkA expression ameliorates cranial radiation-induced neurogenesis impairment and cognitive deficit via PI3K/AKT signaling

Cognitive deficit is one of the most serious complications of cranial radiotherapy of head and neck cancers. However, the underlying mechanism of this cognitive impairment remains unclear. In the present study, the role of tropomyosin receptor kinase A (TrkA) and its ligand neurotrophin nerve growth...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncol Rep
Egile Nagusiak: Ji, Shengjun, Wu, Haohao, Ding, Xin, Chen, Qingqing, Jin, Xing, Yu, Jinming, Yang, Ming
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: D.A. Spandidos 2020
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7640353/
https://ncbi.nlm.nih.gov/pubmed/33125501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2020.7782
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