Pharmacological interrogation of TrkA-mediated mechanisms in hippocampal-dependent memory consolidation

In the brain, the TrkA receptor for Nerve Growth Factor (NGF) is expressed primarily in the cholinergic system. TrkA/NGF support neuronal health and function, and deficiencies in this axis are associated with progressive cholinergic neuron atrophy and death, and with cognitive deficit in disorders s...

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Bibliographic Details
Published in:PLoS One
Main Authors: Josephy-Hernandez, Sylvia, Pirvulescu, Iulia, Maira, Mario, Aboulkassim, Tahar, Wong, Tak Pan, McKinney, R. Anne, Saragovi, H. Uri
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590805/
https://ncbi.nlm.nih.gov/pubmed/31233568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218036
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