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Transient caspase-mediated activation of caspase-activated DNase causes DNA damage required for phagocytic macrophage differentiation
Phagocytic macrophages are crucial for innate immunity and tissue homeostasis. Most tissue-resident macrophages develop from embryonic precursors that populate every organ before birth to lifelong self-renew. However, the mechanisms for versatile macrophage differentiation remain unknown. Here, we u...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2024
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7617294/ https://ncbi.nlm.nih.gov/pubmed/38761374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2024.114251 |
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