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souporcell: Robust clustering of single cell RNAseq by genotype without reference genotypes
Methods to deconvolve single-cell RNA sequencing data are necessary for samples containing a mixture of genotypes whether natural or experimentally combined. Multiplexing across donors is a popular experimental design which can avoid batch effects, reduce costs, and improve doublet detection. Using...
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| Udgivet i: | Nat Methods |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7617080/ https://ncbi.nlm.nih.gov/pubmed/32366989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-020-0820-1 |
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