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M3Drop: dropout-based feature selection for scRNASeq

MOTIVATION: Most genomes contain thousands of genes, but for most functional responses, only a subset of those genes are relevant. To facilitate many single-cell RNASeq (scRNASeq) analyses the set of genes is often reduced through feature selection, i.e. by removing genes only subject to technical n...

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Publicat a:Bioinformatics
Autors principals: Andrews, Tallulah S, Hemberg, Martin
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691329/
https://ncbi.nlm.nih.gov/pubmed/30590489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty1044
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