Repurposing Tamoxifen for Tumor Microenvironment Priming and Enhanced Tumor-Targeted Drug Delivery

The dense stromal matrix in fibrotic tumors hinders tumor-targeted drug delivery. Tamoxifen (TMX), an estrogen receptor modulator that is clinically used for the treatment of breast cancer, has been shown to reprogram the tumor microenvironment (TME) and to alleviate desmoplasia. We here investigate...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Adv Ther (Weinh)
Egile Nagusiak: Biancacci, Ilaria, De Santis, Daniele, Rama, Elena, Benderski, Karina, Momoh, Jeffrey, Pohlberger, Robert, Moeckel, Diana, Kaps, Leonard, Rijcken, Cristianne JF, Prakash, Jai, Thewissen, Marielle, Kiessling, Fabian, Shi, Yang, Peña, Quim, Sofias, Alexandros Marios, Consolino, Lorena, Lammers, Twan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2023
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616667/
https://ncbi.nlm.nih.gov/pubmed/39376929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adtp.202300098
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