Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer

Chemotherapies administered at normal therapeutic dosages can cause significant side-effects and may result in early treatment discontinuation. Inter-individual variation in toxicity highlights the need for biomarkers to personalise treatment. We sought to identify such biomarkers by conducting 40 g...

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Udgivet i:Int J Cancer
Main Authors: Watts, Katie, Wills, Christopher, Madi, Ayman, Palles, Claire, Maughan, Timothy S., Kaplan, Richard, Al-Tassan, Nada A., Kerr, Rachel, Kerr, David, Gray, Victoria, West, Hannah, Houlston, Richard S., Escott-Price, Valentina, Cheadle, Jeremy P.
Format: Artigo
Sprog:Inglês
Udgivet: 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616640/
https://ncbi.nlm.nih.gov/pubmed/34270794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.33739
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