Pattern Recognition Receptor Polymorphisms as Predictors of Oxaliplatin Benefit in Colorectal Cancer

BACKGROUND: Constitutional loss of function (LOF) single nucleotide polymorphisms (SNPs) in pattern recognition receptors FPR1, TLR3, and TLR4 have previously been reported to predict oxaliplatin benefit in colorectal cancer. Confirmation of this association could substantially improve patient strat...

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Publicat a:J Natl Cancer Inst
Autors principals: Gray, Victoria, Briggs, Sarah, Palles, Claire, Jaeger, Emma, Iveson, Timothy, Kerr, Rachel, Saunders, Mark P, Paul, James, Harkin, Andrea, McQueen, John, Summers, Matthew G, Johnstone, Elaine, Wang, Haitao, Gatcombe, Laura, Maughan, Timothy S, Kaplan, Richard, Escott-Price, Valentina, Al-Tassan, Nada A, Meyer, Brian F, Wakil, Salma M, Houlston, Richard S, Cheadle, Jeremy P, Tomlinson, Ian, Church, David N
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695319/
https://ncbi.nlm.nih.gov/pubmed/30649440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djy215
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