Pattern Recognition Receptor Polymorphisms as Predictors of Oxaliplatin Benefit in Colorectal Cancer

BACKGROUND: Constitutional loss of function (LOF) single nucleotide polymorphisms (SNPs) in pattern recognition receptors FPR1, TLR3, and TLR4 have previously been reported to predict oxaliplatin benefit in colorectal cancer. Confirmation of this association could substantially improve patient strat...

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Опубликовано в: :J Natl Cancer Inst
Главные авторы: Gray, Victoria, Briggs, Sarah, Palles, Claire, Jaeger, Emma, Iveson, Timothy, Kerr, Rachel, Saunders, Mark P, Paul, James, Harkin, Andrea, McQueen, John, Summers, Matthew G, Johnstone, Elaine, Wang, Haitao, Gatcombe, Laura, Maughan, Timothy S, Kaplan, Richard, Escott-Price, Valentina, Al-Tassan, Nada A, Meyer, Brian F, Wakil, Salma M, Houlston, Richard S, Cheadle, Jeremy P, Tomlinson, Ian, Church, David N
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695319/
https://ncbi.nlm.nih.gov/pubmed/30649440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djy215
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